Volume 6, Issue 1 (3-2018)
Abstract
(12272 Views) |
Full-Text (PDF)
(4171 Downloads)
|
Graphical Abstract
|
Highlights
- It has been suggested that various epigenetic deviations play a major role in the pathogenesis of endometriosis.
- Steroidogenic factor 1 (SF-1; NR5A1) is an essential transcription factor for estrogen biosynthesis in endometrial cells.
- Here, we aimed to compare the methylation status of the SF-1 gene promoter region in women with endometriosis in comparison to healthy subjects.
- The methylation status of SF-1 gene promoter was decreased significantly in endometriosis samples.
- SF-1 gene promoter hypomethylation could increase the relative expression of SF-1 gene in endometriosis which may lead to the development or progression of the disease.
Abstract
(12568 Views) |
Full-Text (PDF)
(4377 Downloads)
Abstract
(18202 Views) |
Full-Text (PDF)
(4458 Downloads)
Abstract
(19951 Views) |
Full-Text (PDF)
(4511 Downloads)
Abstract
(11589 Views) |
Full-Text (PDF)
(4416 Downloads)
Abstract
(19335 Views) |
Full-Text (PDF)
(4445 Downloads)
Abstract
(16990 Views) |
Full-Text (PDF)
(4101 Downloads)
Export as:
HTML
|
XML
|
RSS