Volume 6, Issue 1 (3-2018)
Abstract
(11967 Views) |
Full-Text (PDF)
(4061 Downloads)
|
Graphical Abstract
|
Highlights
- It has been suggested that various epigenetic deviations play a major role in the pathogenesis of endometriosis.
- Steroidogenic factor 1 (SF-1; NR5A1) is an essential transcription factor for estrogen biosynthesis in endometrial cells.
- Here, we aimed to compare the methylation status of the SF-1 gene promoter region in women with endometriosis in comparison to healthy subjects.
- The methylation status of SF-1 gene promoter was decreased significantly in endometriosis samples.
- SF-1 gene promoter hypomethylation could increase the relative expression of SF-1 gene in endometriosis which may lead to the development or progression of the disease.
Abstract
(12204 Views) |
Full-Text (PDF)
(4245 Downloads)
Abstract
(17871 Views) |
Full-Text (PDF)
(4328 Downloads)
Abstract
(19591 Views) |
Full-Text (PDF)
(4380 Downloads)
Abstract
(11311 Views) |
Full-Text (PDF)
(4306 Downloads)
Abstract
(18949 Views) |
Full-Text (PDF)
(4322 Downloads)
Abstract
(16650 Views) |
Full-Text (PDF)
(3993 Downloads)
Export as:
HTML
|
XML
|
RSS