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:: دوره 4، شماره 1 - ( بهار 1395 ) ::
جلد 4 شماره 1 صفحات 14-1 برگشت به فهرست نسخه ها
ترانوستیک (Theranostics) علم کاربرد نانوسیستم ها در درمان هدفمند و تصویربرداری همزمان در بیماری‌ها
پدرام ترابیان، دکتر وحید عرفانی مقدم
استادیار بیوتکنولوژی پزشکی دانشگاه علوم پزشکی گلستان ، vahid.erfani@goums.ac.ir
چکیده:   (2495 مشاهده)

برای ده ها سال محققان تلاش کرده اند روش هایی با مکانیزم های غیر تخریبی (noninvasive) برای بررسی وضعیت بیماری درون بدن بیمار ابداع نمایند. ظهور نانوتکنولوژی این امکان را فراهم نمود. مقیاس نانو توانایی کشف اولیه بیماری را در مراحل سلولی و قبل از این که بافت بیمار یا تومور به وجود آید، فراهم آورده است که می تواند کمک بزرگی برای درمان بیماری ها باشد. در چند سال اخیر، ترانوستیک (Theranostics) به عنوان یکی از جدیدترین نگرش ها در نانو مطرح شده است که عمل شناسایی و درمان و ردیابی پس از درمان همزمان صورت می پذیرد. بنابراین ترانوستیک را می‌توان نوعی راهبرد درمانی مناسبی برای پزشکی شخصی، فارماکوژنومیکس و تصویربرداری مولکولی دانست تا بدین وسیله بتوان راهی در جهت توسعه درمان‌های نوین پدید آورد و با بهره از درک مولکولی بهتر، در انتخاب داروهای مؤثرتری عمل کرد. درنهایت، محققان بر این باورند که ترانوستیک می تواند در پاسخ به درمان‌ها نظارت داشته و ایمنی و درجه تأثیر دارو را افزایش دهد و از درمان‌های نابجای بیماران جلوگیری کند و درنهایت منجر به کاهش بخش زیادی از هزینه‌های درمان در تمام نظام سلامت گردد. در این مطالعه، به طور اجمالی بخش های ساختاری و برخی قابلیت های کاربردی نانوحامل های ترانوستیک بررسی می شود.

واژه‌های کلیدی: ترانوستیک، درمانی، تشخیصی، سیستم های نانوی دارورسانی، چندعملکردی
متن کامل [PDF 855 kb]   (917 دریافت)    
نوع مطالعه: مروری | موضوع مقاله: عمومى
دریافت: ۱۳۹۵/۵/۲۳ | پذیرش: ۱۳۹۵/۵/۲۳ | انتشار: ۱۳۹۵/۵/۲۳
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Torabian P, Erfani-Moghadam V. Theranostics; Application of Nanosystems for Simultaneous Targeted Therapy and Imaging in Diseases. Hakim Jorjani J. 2016; 4 (1) :14-1
URL: http://goums.ac.ir/jorjanijournal/article-1-437-fa.html
ترابیان پدرام، عرفانی مقدم وحید. ترانوستیک (Theranostics) علم کاربرد نانوسیستم ها در درمان هدفمند و تصویربرداری همزمان در بیماری‌ها. مجله حکیم سیداسماعیل جرجانی. 1395; 4 (1) :14-1

URL: http://goums.ac.ir/jorjanijournal/article-1-437-fa.html

دوره 4، شماره 1 - ( بهار 1395 ) برگشت به فهرست نسخه ها
مجله حکیم جرجانی jorjani
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