Volume 4, Issue 1 (5-2016)
Jorjani Biomed J 2016, 4(1): 14-1 |
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Torabian P, Erfani-Moghadam V. Theranostics; Application of Nanosystems for Simultaneous Targeted Therapy and Imaging in Diseases. Jorjani Biomed J 2016; 4 (1) :14-1
URL: http://goums.ac.ir/jorjanijournal/article-1-437-en.html
URL: http://goums.ac.ir/jorjanijournal/article-1-437-en.html
1- Golestan University of Medical Sciences
2- Golestan University of Medical Sciences ,vahid.erfani@goums.ac.ir
2- Golestan University of Medical Sciences ,
Abstract: (16259 Views)
For decades, researchers have tried to develop non-invasive mechanisms for monitoring pathological conditions within the body of patients. Emerging nanotechnology enabled us to reach this aim. Scale of nano has the potential to increase early detection of pathological conditions among abnormal cells before diseased tissue or tumor development can be considerable which is helpful in disease treatment. In recent years, “Theranostics” has been emerged as a novel nano approach which performs diagnostic detection, therapy and follows up simultaneously. Therefore, Theranostics can be considered as an appropriate therapeutic approach for personalized medicine, pharmacogenomics and molecular imaging which can open a gate to develop novel therapies. Additionally, with a deeper molecular understanding, choosing drugs that are more effective will be possible. Finally, researchers believe that Theranostics has the potential to monitor treatments by increasing drug effectiveness and preventing inappropriate treatments and consequently reducing the cost of national health burden. In this review, structure and some applications of Theranostics and nano drug delivery systems have been discussed briefly.
Keywords: Theranostics, Therapeutic, Diagnostic, Nanoparticulate drug delivery systems (NDDSs), Multifunctional
Type of Article: Review Article |
Subject:
General medicine
Received: 2016/08/13 | Accepted: 2016/08/13 | Published: 2016/08/13
Received: 2016/08/13 | Accepted: 2016/08/13 | Published: 2016/08/13
References
1. Torchilin VP. Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery. Nat Rev Drug Discov. 2014;13(11):813-27.
2. Lim E-K, Kim T, Paik S, Haam S, Huh Y-M, Lee K. Nanomaterials for Theranostics: Recent Advances and Future Challenges. Chemical reviews. 2014;115(1):327-94.
3. Caldorera-Moore ME, Liechty WB, Peppas NA. Responsive theranostic systems: integration of diagnostic imaging agents and responsive controlled release drug delivery carriers. Acc Chem Res. 2011;44(10):1061-70.
4. Torchilin VP. Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery. Nature Reviews Drug Discovery. 2014;13(11):813-27.
5. Eck W, Craig G, Sigdel A, Ritter G, Old LJ, Tang L, et al. PEGylated gold nanoparticles conjugated to monoclonal F19 antibodies as targeted labeling agents for human pancreatic carcinoma tissue. Acs Nano. 2008;2(11):2263-72.
6. Hu K, Li J, Shen Y, Lu W, Gao X, Zhang Q, et al. Lactoferrin-conjugated PEG–PLA nanoparticles with improved brain delivery: in vitro and in vivo evaluations. Journal of controlled release. 2009;134(1):55-61.
7. Psarros C, Lee R, Margaritis M, Antoniades C. Nanomedicine for the prevention, treatment and imaging of atherosclerosis. Nanomedicine. 2012;8 Suppl 1:S59-68.
8. Peters D, Kastantin M, Kotamraju VR, Karmali PP, Gujraty K, Tirrell M, et al. Targeting atherosclerosis by using modular, multifunctional micelles. Proc Natl Acad Sci U S A. 2009;106(24):9815-9.
9. Broz P, Ben-Haim N, Grzelakowski M, Marsch S, Meier W, Hunziker P. Inhibition of macrophage phagocytotic activity by a receptor-targeted polymer vesicle-based drug delivery formulation of pravastatin. J Cardiovasc Pharmacol. 2008;51(3):246-52.
10. Bowey K, Tanguay JF, Tabrizian M. Liposome technology for cardiovascular disease treatment and diagnosis. Expert Opin Drug Deliv. 2012;9(2):249-65.
11. Guo Y, Chen W, Wang W, Shen J, Guo R, Gong F, et al. Simultaneous diagnosis and gene therapy of immuno-rejection in rat allogeneic heart transplantation model using a T-cell-targeted theranostic nanosystem. ACS Nano. 2012;6(12):10646-57.
12. McCarthy JR, Sazonova IY, Erdem SS, Hara T, Thompson BD, Patel P, et al. Multifunctional nanoagent for thrombus-targeted fibrinolytic therapy. Nanomedicine (Lond). 2012;7(7):1017-28.
13. Mehendale R, Joshi M, Patravale VB. Nanomedicines for treatment of viral diseases. Crit Rev Ther Drug Carrier Syst. 2013;30(1):1-49.
14. Xiong MH, Li YJ, Bao Y, Yang XZ, Hu B, Wang J. Bacteria-responsive multifunctional nanogel for targeted antibiotic delivery. Adv Mater. 2012;24(46):6175-80.
15. Mihu MR, Sandkovsky U, Han G, Friedman JM, Nosanchuk JD, Martinez LR. The use of nitric oxide releasing nanoparticles as a treatment against Acinetobacter baumannii in wound infections. Virulence. 2010;1(2):62-7.
16. Banerjee M, Mallick S, Paul A, Chattopadhyay A, Ghosh SS. Heightened Reactive Oxygen Species Generation in the Antimicrobial Activity of a Three Component Iodinated Chitosan− Silver Nanoparticle Composite. Langmuir. 2010;26(8):5901-8.
17. Gabizon A, Shmeeda H, Horowitz AT, Zalipsky S. Tumor cell targeting of liposome-entrapped drugs with phospholipid-anchored folic acid-PEG conjugates. Adv Drug Deliv Rev. 2004;56(8):1177-92.
18. Niu R, Zhao P, Wang H, Yu M, Cao S, Zhang F, et al. Preparation, characterization, and antitumor activity of paclitaxel-loaded folic acid modified and TAT peptide conjugated PEGylated polymeric liposomes. J Drug Target. 2011;19(5):373-81.
19. Chaudhury A, Das S, Bunte RM, Chiu GN. Potent therapeutic activity of folate receptor-targeted liposomal carboplatin in the localized treatment of intraperitoneally grown human ovarian tumor xenograft. Int J Nanomedicine. 2012;7:739-51
20. Duarte S, Faneca H, Lima MC. Folate-associated lipoplexes mediate efficient gene delivery and potent antitumoral activity in vitro and in vivo. Int J Pharm. 2012;423(2):365-77.
21. Cheng KT, Wang PC, Shan L. Alexa Fluor 680-labeled transferrin-cationic (NBD-labeled DOPE-DOTAP) liposome-encapsulated gadopentetate dimeglumine complex. Molecular Imaging and Contrast Agent Database (MICAD). Bethesda (MD)2004.
22. Danhier F, Feron O, Preat V. To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery. J Control Release. 2010;148(2):135-46.
23. Gabizon A, Tzemach D, Gorin J, Mak L, Amitay Y, Shmeeda H, et al. Improved therapeutic activity of folate-targeted liposomal doxorubicin in folate receptor-expressing tumor models. Cancer Chemother Pharmacol. 2010;66(1):43-52.
24. Riviere K, Huang Z, Jerger K, Macaraeg N, Szoka FC, Jr. Antitumor effect of folate-targeted liposomal doxorubicin in KB tumor-bearing mice after intravenous administration. J Drug Target. 2011;19(1):14-24.
25. Niu R, Zhao P, Wang H, Yu M, Cao S, Zhang F, et al. Preparation, characterization, and antitumor activity of paclitaxel-loaded folic acid modified and TAT peptide conjugated PEGylated polymeric liposomes. Journal of drug targeting. 2011;19(5):373-81.
26. Hatakeyama H, Akita H, Ishida E, Hashimoto K, Kobayashi H, Aoki T, et al. Tumor targeting of doxorubicin by anti-MT1-MMP antibody-modified PEG liposomes. Int J Pharm. 2007;342(1-2):194-200.
27. Mura S, Nicolas J, Couvreur P. Stimuli-responsive nanocarriers for drug delivery. Nat Mater. 2013;12(11):991-1003.
28. Sawant RR, Sriraman SK, Navarro G, Biswas S, Dalvi RA, Torchilin VP. Polyethyleneimine-lipid conjugate-based pH-sensitive micellar carrier for gene delivery. Biomaterials. 2012;33(15):3942-51.
29. Sawant RM, Hurley JP, Salmaso S, Kale A, Tolcheva E, Levchenko TS, et al.
30. Helmlinger G, Sckell A, Dellian M, Forbes NS, Jain RK. Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism. Clin Cancer Res. 2002;8(4):1284-91.
31. Wojtkowiak JW, Verduzco D, Schramm KJ, Gillies RJ. Drug resistance and cellular adaptation to tumor acidic pH microenvironment. Mol Pharm. 2011;8(6):2032-8.
32. Lee ES, Shin HJ, Na K, Bae YH. Poly(L-histidine)-PEG block copolymer micelles and pH-induced destabilization. J Control Release. 2003;90(3):363-74.
33. Farhood H, Serbina N, Huang L. The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acta. 1995;1235(2):289-95.
34. Dong D-W, Xiang B, Gao W, Yang Z-Z, Li J-Q, Qi X-R. pH-responsive complexes using prefunctionalized polymers for synchronous delivery of doxorubicin and siRNA to cancer cells. Biomaterials. 2013;34(20):4849-59.
35. Kim T-i, Ou M, Lee M, Kim SW. Arginine-grafted bioreducible poly (disulfide amine) for gene delivery systems. Biomaterials. 2009;30(4):658-64.
36. Vader P, van der Aa LJ, Engbersen JF, Storm G, Schiffelers RM. Disulfide-based poly (amido amine) s for siRNA delivery: effects of structure on siRNA complexation, cellular uptake, gene silencing and toxicity. Pharmaceutical research. 2011;28(5):1013-22.
37. Kurtoglu YE, Navath RS, Wang B, Kannan S, Romero R, Kannan RM. Poly (amidoamine) dendrimer–drug conjugates with disulfide linkages for intracellular drug delivery. Biomaterials. 2009;30(11):2112-21.
38. Wong C, Stylianopoulos T, Cui J, Martin J, Chauhan VP, Jiang W, et al. Multistage nanoparticle delivery system for deep penetration into tumor tissue. Proceedings of the National Academy of Sciences. 2011;108(6):2426-31.
39. Kang H, Trondoli AC, Zhu G, Chen Y, Chang Y-J, Liu H, et al. Near-infrared light-responsive core–shell nanogels for targeted drug delivery. Acs Nano. 2011;5(6):5094-9.
40. Pradhan P, Giri J, Rieken F, Koch C, Mykhaylyk O, Döblinger M, et al. Targeted temperature sensitive magnetic liposomes for thermo-chemotherapy. Journal of Controlled Release. 2010;142(1):108-21.
41. Sherlock SP, Tabakman SM, Xie L, Dai H. Photothermally enhanced drug delivery by ultrasmall multifunctional FeCo/graphitic shell nanocrystals. Acs Nano. 2011;5(2):1505-12.
42. Schroeder A, Honen R, Turjeman K, Gabizon A, Kost J, Barenholz Y. Ultrasound triggered release of cisplatin from liposomes in murine tumors. Journal of Controlled Release. 2009;137(1):63-8.
43. Liao C, Sun Q, Liang B, Shen J, Shuai X. Targeting EGFR-overexpressing tumor cells using Cetuximab-immunomicelles loaded with doxorubicin and superparamagnetic iron oxide. European journal of radiology. 2011;80(3):699-705.
44. Liu D, Wu W, Chen X, Wen S, Zhang X, Ding Q, et al. Conjugation of paclitaxel to iron oxide nanoparticles for tumor imaging and therapy. Nanoscale. 2012;4(7):2306-10.
45. Sun L, Yang Y, Dong CM, Wei Y. Two‐Photon‐Sensitive and Sugar‐Targeted Nanocarriers from Degradable and Dendritic Amphiphiles. Small. 2011;7(3):401-6.
46. Wen CJ, Zhang LW, Al-Suwayeh SA, Yen TC, Fang JY. Theranostic liposomes loaded with quantum dots and apomorphine for brain targeting and bioimaging. Int J Nanomedicine. 2012;7:1599-611.
47. Kenny GD, Bienemann AS, Tagalakis AD, Pugh JA, Welser K, Campbell F, et al. Multifunctional receptor-targeted nanocomplexes for the delivery of therapeutic nucleic acids to the brain. Biomaterials. 2013;34(36):9190-200.
48. Lee PW, Hsu SH, Tsai JS, Chen FR, Huang PJ, Ke CJ, et al. Multifunctional core-shell polymeric nanoparticles for transdermal DNA delivery and epidermal Langerhans cells tracking. Biomaterials. 2010;31(8):2425-34.
49. Elbayoumi TA, Torchilin VP. Enhanced cytotoxicity of monoclonal anticancer antibody 2C5-modified doxorubicin-loaded PEGylated liposomes against various tumor cell lines. Eur J Pharm Sci. 2007;32(3):159-68.
50. Lee N, Yoo D, Ling D, Cho MH, Hyeon T, Cheon J. Iron Oxide Based Nanoparticles for Multimodal Imaging and Magnetoresponsive Therapy. Chem Rev. 2015;115(19):10637-89.
51. Thomas R, Park IK, Jeong YY. Magnetic iron oxide nanoparticles for multimodal imaging and therapy of cancer. Int J Mol Sci. 2013;14(8):15910-30.
52. Kim TJ, Chae KS, Chang Y, Lee GH. Gadolinium oxide nanoparticles as potential multimodal imaging and therapeutic agents. Curr Top Med Chem. 2013;13(4):422-33.
53. Sandiford L, Phinikaridou A, Protti A, Meszaros LK, Cui X, Yan Y, et al. Bisphosphonate-anchored PEGylation and radiolabeling of superparamagnetic iron oxide: long-circulating nanoparticles for in vivo multimodal (T1 MRI-SPECT) imaging. ACS Nano. 2013;7(1):500-12.
54. Heidt T, Nahrendorf M. Multimodal iron oxide nanoparticles for hybrid biomedical imaging. NMR Biomed. 2013;26(7):756-65.
55. Yang L, Peng XH, Wang YA, Wang X, Cao Z, Ni C, et al. Receptor-targeted nanoparticles for in vivo imaging of breast cancer. Clin Cancer Res. 2009;15(14):4722-32.
56. Medarova Z, Pham W, Farrar C, Petkova V, Moore A. In vivo imaging of siRNA delivery and silencing in tumors. Nat Med. 2007;13(3):372-7.
57. Koo H, Lee H, Lee S, Min KH, Kim MS, Lee DS, et al. In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles. Chem Commun (Camb). 2010;46(31):5668-70.
58. Kenny GD, Kamaly N, Kalber TL, Brody LP, Sahuri M, Shamsaei E, et al. Novel multifunctional nanoparticle mediates siRNA tumour delivery, visualisation and therapeutic tumour reduction in vivo. J Control Release. 2011;149(2):111-6.
59. Koning GA, Krijger GC. Targeted multifunctional lipid-based nanocarriers for image-guided drug delivery. Anticancer Agents Med Chem. 2007;7(4):425-40.
60. Sajja HK, East MP, Mao H, Wang YA, Nie S, Yang L. Development of multifunctional nanoparticles for targeted drug delivery and noninvasive imaging of therapeutic effect. Curr Drug Discov Technol. 2009;6(1):43-51.
61. Briel A, Reinhardt M, Mäurer M, Hauff P. Ultrasound Theranostics: Antibody-based Microbubble Conjugates as Targeted In vivo Contrast Agents and Advanced Drug Delivery Systems. Modern Biopharmaceuticals: Wiley-VCH Verlag GmbH; 2008. p. 1301-24.
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