Volume 8, Issue 4 (12-2020)                   Jorjani Biomed J 2020, 8(4): 26-33 | Back to browse issues page

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Yeganegi M, Behnampour A, Mirzaei F, Tabrizi A, Zokaee H. Psychological status in Head and Neck Cancer Patients with Xerostomia due to Radiotherapy. Jorjani Biomed J. 2020; 8 (4) :26-33
URL: http://goums.ac.ir/jorjanijournal/article-1-765-en.html
1- General Dentist, Gorgan, Iran
2- Golestan University of Medical Sciences, Gorgan, Iran
3- Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran
4- Dental Research Center, Golestan University of Medical Sciences, Gorgan , halehzokaee2020@gmail.com
Abstract:   (93 Views)
Background and objective: Psychological status is one of the quality of life (QOL) domains which can be affected by hyposalivation caused by head and neck radiotherapy. This study aimed to evaluate the psychological status of head and neck cancer (HNC) patients who were suffering from hyposalivation after at least one week of receiving radiotherapy.
Material And Methods: This descriptive-analytic study was performed on 44 HNC patients with history of hyposalivation caused by radiotherapy, in 5 Azar hospital from 1397-1398. General Health Questionnaire (GHQ-28) was used for data collection. Shapiro-Wilk test, parametric and nonparametric tests and SPSS 18 software were used for statistical analysis.
Results: The average psychological status of patients was 27.50 out of 84 (lower score indicated better psychological status). The mean score of physical health was 7.39, social functioning was 6.16, anxiety/insomnia were 12.64 and depression was 1.33 with the maximum being 21. Psychological status was not significantly different between genders. Ageing caused all subscales to increase except depression. A direct relationship between social functionality and psychological status was reported.
Conclusion: Hyposalivation due to radiotherapy affects psychological status and its components in patients. Also, various factors such as ageing and lower education level can be effective in reducing psychological status in the patients with head and neck cancer who were suffering from hyposalivation due to receiving radiotherapy.
Full-Text [PDF 548 kb]   (32 Downloads)    
Type of Article: Brief Report | Subject: General medicine
Received: 2020/10/1 | Accepted: 2020/10/15 | Published: 2020/11/30

References
1. Fitzmaurice C, Allen C, Barber RM, Barregard L, Bhutta ZA, Brenner H, et al. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: a systematic analysis for the global burden of disease study. JAMA Oncol. 2017;3(4):524-48. [DOI:10.1001/jamaoncol.2016.5688]
2. Walden MJ, Aygun N. Head and neck cancer. Semin Roentgenol. 2013;48(1):75-86. [DOI:10.1053/j.ro.2012.09.002]
3. Kırca K, Kutlutürkan S. Symptoms of patients with head and neck cancers undergoing radiotherapy. Eur J Cancer Care (Engl). 2017;26.(6). [DOI:10.1111/ecc.12584]
4. Braam PM, Terhaard CH, Roesink JM, Raaijmakers CP. Intensity-modulated radiotherapy significantly reduces xerostomia compared with conventional radiotherapy. Int J Radiat Oncol Biol Phys. 2006;66(4):975-80. [DOI:10.1016/j.ijrobp.2006.06.045]
5. Lopez-Jornet P, Lucero Berdugo M, Fernandez-Pujante A, Lavella C Z, Silvestre FJ. Sleep quality in patients with xerostomia: a prospective and randomized case-control study. Acta Odontol Scand. 2016;74(3):224-8. [DOI:10.3109/00016357.2015.1099730]
6. Wijers OB, Levendag PC, Braaksma MM, Boonzaaijer M, Visch LL, Schmitz PI. Patients with head and neck cancer cured by radiation therapy: A survey of the dry mouth syndrome in long‐term survivors. Head Neck. 2002;24(8):737-47. [DOI:10.1002/hed.10129]
7. Almståhl A, Alstad T, Fagerberg‐Mohlin B, Carlén A, Finizia C. Explorative study on quality of life in relation to salivary secretion rate in patients with head and neck cancer treated with radiotherapy. Head Neck. 2016;38(5):782-91. [DOI:10.1002/hed.23964]
8. Allal AS, Dulguerov P, Bieri S, Lehmann W, Kurtz JM. Assessment of quality of life in patients treated with accelerated radiotherapy for laryngeal and hypopharyngeal carcinomas. Head Neck. 2000;22(3):288-93. https://doi.org/10.1002/(SICI)1097-0347(200005)22:3<288::AID-HED12>3.0.CO;2-B [DOI:10.1002/(SICI)1097-0347(200005)22:33.0.CO;2-B]
9. World Health Organization. WHOQOL-BREF: introduction, administration, scoring and generic version of the assessment: field trial version, December 1996. World Health Organization; 1996.
10. Robinson D, Renshaw C, Okello C, Møller H, Davies E. Suicide in cancer patients in South East England from 1996 to 2005: a population-based study. Br J Cancer. 2009;101(1):198-201. [DOI:10.1038/sj.bjc.6605110]
11. Kallay E, Dégi CL, Vincze AE. Dysfunctional attitudes, depression and quality of life in a sample of Romanian. J Cogn Behav Psychother. 2007;7(1):95-106.
12. Rabiei M, Rahimi A, Kazemnezhad Leyli E, Jalalian B, Massoudi Rad S. Complication of post radiation in patients with head and neck cancer. J Gorgan Univ Med Sci. 2014;16(2):114-20.
13. Chambers MS, Garden AS, Kies MS, Martin JW. Radiation‐induced xerostomia in patients with head and neck cancer: pathogenesis, impact on quality of life, and management. Head Neck. 2004;26(9):796-807. [DOI:10.1002/hed.20045]
14. Duncan GG, Epstein JB, Tu D, Sayed SE, Bezjak A, Ottaway J, et al. Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: a report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis. Head Neck. 2005;27(5):421-8. [DOI:10.1002/hed.20162]
15. Pow EH, Kwong DL, McMillan AS, Wong MC, Sham JS, Leung LH, et al. Xerostomia and quality of life after intensity-modulated radiotherapy vs. conventional radiotherapy for early-stage nasopharyngeal carcinoma: initial report on a randomized controlled clinical trial. Int J Radiat Oncol Biol Phys. 2006;66(4):981-91. [DOI:10.1016/j.ijrobp.2006.06.013]
16. Agha-Hosseini F, Mirzaii-Dizgah I, Mirjalili N. Serum cortisol level in menopausal women with dry mouth. J Islam Dent Assoc Iran. 2010;22(3).
17. Torres SR, Peixoto CB, Caldas DM, Silva EB, Akiti T, Nucci M, et al. Relationship between salivary flow rates and Candida counts in subjects with xerostomia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;93(2):149-54. [DOI:10.1067/moe.2002.119738]
18. Glick M, William M. Burket's Oral medicine 12th ed. Shelton, CT: PMPH-USA Ltd. 2015. P. 250.
19. Goldberg D. Manual of the general health questionnaire: Nfer Nelson; 1978.
20. Nazifi M, Mokarami H, Akbaritabar A, FarajiKujerdi M, Tabrizi R, Rahi A. Reliability, validity and factor structure of the persian translation of general health questionnire (ghq-28) in hospitals of kerman university of medical sciences. J FasaUniv Med Sci. 2014;3:336-42. [DOI:10.17795/jhealthscope-15547]
21. Ebrahimi A, Molavi H, Moosavi G, Bornamanesh A, Yaghobi M. Psychometric Properties and Factor Structure of General Health Questionnaire 28 (GHQ-28) in Iranian Psychiatric Patients. J Res Behav Sci. 2007;5(1):5-11.
22. Astrup GL, Rustøen T, Hofsø K, Gran JM, Bjordal K. Symptom burden and patient characteristics: Association with quality of life in patients with head and neck cancer undergoing radiotherapy. Head Neck. 2017;39(10):2114-26. [DOI:10.1002/hed.24875]
23. Neilson K, Pollard A, Boonzaier A, Corry J, Castle D, Smith D, et al. A longitudinal study of distress (depression and anxiety) up to 18 months after radiotherapy for head and neck cancer. Psychooncology. 2013;22(8):1843-8. [DOI:10.1002/pon.3228]
24. Pelland M, Lambert L, Filion E, Bahig H, Beaudry M, Ouellette A, et al., editors. Depression, anxiety and claustrophobia in patients undergoing radiotherapy for head and neck cancer. RadiotherOncol. 2017 May 1;123(2):318-9. [DOI:10.1016/S0167-8140(17)31045-9]
25. Lee Y, Wu Y-S, Chien C-Y, Fang F-M, Hung C-F. Use of the Hospital Anxiety and Depression Scale and the Taiwanese Depression Questionnaire for screening depression in head and neck cancer patients in Taiwan. Neuropsychiatr Dis Treat. 2016;12:2649. [DOI:10.2147/NDT.S112069]
26. Wu Y-s, Lin P-Y, Chien C-Y, Fang F-M, Chiu N-M, Hung C-F, et al. Anxiety and depression in patients with head and neck cancer: 6-month follow-up study. Neuropsychiatr Dis Treat. 2016;12:1029. [DOI:10.2147/NDT.S103203]
27. Nikoloudi M, Lymvaios I, Zygogianni A, Parpa E, Strikou D-A, Tsilika E, et al. Quality of life, anxiety, and depression in the head-and-neck cancer patients, undergoing intensity-modulated radiotherapy treatment. Indian J Palliat Care. 2020;26(1):54. [DOI:10.4103/IJPC.IJPC_168_19]
28. Malekian A, Alizadeh A, Ahmadzadeh GH. Anxiety and Depression in Cancer Patients. J Res Behavior Sci. 2007;5:115-118.
29. Rajabizadeh G, Mansoori SM, Shakibi MR, Ramazani MR. Determination of Factors Related to Depression in Cancer Patients of the Oncology Ward in Kerman. J Kerman Univ Med Sci. 2005;12(2):142-7.
30. Linden W, Vodermaier A, MacKenzie R, Greig D. Anxiety and depression after cancer diagnosis: prevalence rates by cancer type, gender, and age. J Affect Disord. 2012;141(2-3):343-51. [DOI:10.1016/j.jad.2012.03.025]
31. Naseri N, Taleghani F. Depression in cancer patients: the role of demographic variables. Iran J Cancer Nurs. 2019;1(1):55-61. [DOI:10.29252/ijca.1.1.55]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


© 2021 All Rights Reserved | Jorjani Biomedicine Journal

Designed & Developed by : Yektaweb