Volume 7, Issue 1 (January-March 2019)                   Jorjani Biomed J 2019, 7(1): 1-13 | Back to browse issues page

DOI: 10.29252/jorjanibiomedj.7.1.1

XML Print

1- Department of Endodontics, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2- Department of Endodontics, School of dentistry, Shahid Sadoughi University of Medical Sciences, Yazd , Iran , hakimianr@gmail.com
Abstract:   (687 Views)
Nano science and nanotechnology have revolutionized all aspects in the endodontic field. The aim of the present study was to describe the application of nanotechnology in endodontics by reviewing the literature.The application of nanomaterials, with a smaller size, for surface modification has reduced the incidence of failure in the rotary nickel-titanium files. Nanoparticles with the ability of rapid dispersion into the hard-to-reach spaces in the complex root canal system have a better antimicrobial effect. The incorporation of nanoparticles in the obturating materials promotes the sealing properties and antimicrobial efficacy. Nanoscaffolds in the pulp regeneration approaches, bioceramics as retrofilling, and repair materials, and Nanorobots and nanoterminators as new technologies for local anesthesia with fewer side effects are some examples in this regard.
Full-Text [PDF 978 kb]   (206 Downloads)    
Type of Article: Review Article | Subject: Basic Medical Sciences
Received: 2019/01/12 | Revised: 2020/01/27 | Accepted: 2019/02/20

1. Feynman RP. There's plenty of room at the bottom. Engineering and science 1960;23(5):22-36.
2. Drexler KE. Engine of creation: The Coming Era of Nanotechnology. New Yourk: Anchor Press; 1986.
3. Patil M, Mehta DS, Guvva S. Future impact of nanotechnology on medicine and dentistry. J Indian Soc Periodontol 2008;12(2):34- 40. [DOI:10.4103/0972-124X.44088]
4. Uskoković V, Bertassoni LE. Nanotechnology in dental sciences: moving towards a finer way of doing dentistry. Materials 2010;3(3):1674-1691. [DOI:10.3390/ma3031674]
5. Jurczyka K, Jurczykb M. Introducion. In: Jurczykb M, editor. Bionanomaterials for Dental Applications. Boca Raton: CRC press; 2012. p. 1- 11.
6. Dowling AP. Development of nanotechnologies. Materials Today 2004;7(12):30-35. [DOI:10.1016/S1369-7021(04)00628-5]
7. Dwivedi S, Dwivedi CD, Chandra A, Sharma N. Nanotechnology boon or bane for restorative dentistry; A review. Inte J Eng Sci Inv 2013;2(1):1-5. [DOI:10.4103/2278-9626.106827]
8. An J, Chua CK, Yu T, Li H, Tan LP. Advanced nanobiomaterial strategies for the development of organized tissue engineering constructs. Nanomedicine (Lond) 2013;8(4):591- 602. [DOI:10.2217/nnm.13.46]
9. Teo WE, Liao S, Chan C, Ramakrishna S. Fabrication and characterization of hierarchically organized nanoparticle-reinforced nanofibrous composite scaffolds. Acta Biomater 2011;7(1):193-202. [DOI:10.1016/j.actbio.2010.07.041]
10. Freitas RA, Jr. Nanotechnology, nanomedicine and nanosurgery. Int J Surg 2005;3(4):243-6. [DOI:10.1016/j.ijsu.2005.10.007]
11. Nagpal A, Kaur J, Sharma S, Bansal A. Nanotechnology-the era of molecular Dentistry. Indian J Dent Res 2011;3(5):80-82.
12. Fioretti F, Mendoza-Palomares C, Helms M, Al Alam D, Richert L, Arntz Y, et al. Nanostructured assemblies for dental application. ACS Nano 2010;4(6):3277-87. [DOI:10.1021/nn100713m]
13. Kazemipoor M, Tabrizizadeh M, Dastani M, Hakimian R. The effect of retreatment procedure on the pH changes at the surface of root dentin using two different calcium hydroxide pastes. J Conserv Dent 2012;15(4):346-50. [DOI:10.4103/0972-0707.101899]
14. Tabrizizadeh M, Kazemipoor M, Hekmati-Moghadam S-H, Hakimian R. Impact of root canal preparation size and taper on coronalapical micro-leakage using glucose penetration method. J Clin Exper Dent 2014;6(4):344-349. [DOI:10.4317/jced.51452]
15. Chogle SM, Duhaime CF, Mickel AK, Shaikh S, Reese R, Bogle JH, et al. Preliminary evaluation of a novel polymer nanocomposite as a root-end filling material. Int Endod J 2011;44(11):1055-60. [DOI:10.1111/j.1365-2591.2011.01921.x]
16. Gomes-Filho JE, Silva FO, Watanabe S, Cintra LT, Tendoro KV, Dalto LG, et al. Tissue reaction to silver nanoparticles dispersion as an alternative irrigating solution. J Endod 2010;36(10):1698-702. [DOI:10.1016/j.joen.2010.07.007]
17. Kesler Shvero D, Abramovitz I, Zaltsman N, Perez Davidi M, Weiss EI, Beyth N. Towards antibacterial endodontic sealers using quaternary ammonium nanoparticles. Int Endod J 2013;46(8):747-54. [DOI:10.1111/iej.12054]
18. Meechan JG. Intra-oral topical anaesthetics: a review. J Dent 2000;28(1):3-14. [DOI:10.1016/S0300-5712(99)00041-X]
19. Andreasen GF, Morrow RE. Laboratory and clinical analyses of nitinol wire. Am J Orthod 1978;73(2):142-51. [DOI:10.1016/0002-9416(78)90184-7]
20. Walia HM, Brantley WA, Gerstein H. An initial investigation of the bending and torsional properties of Nitinol root canal files. J Endod 1988;14(7):346-51. [DOI:10.1016/S0099-2399(88)80196-1]
21. Peters OA, Paque F. Current developments in rotary root canal instrument technology and clinical use: a review. Quintessence Int 2010;41(6):479-88.
22. Zuolo ML, Walton RE. Instrument deterioration with usage: nickel-titanium versus stainless steel. Quintessence Int 1997;28(6):397- 402.
23. Rapisarda E, Bonaccorso A, Tripi TR, Fragalk I, Condorelli GG. The effect of surface treatments of nickel-titanium files on wear and cutting efficiency. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89(3):363-8. [DOI:10.1016/S1079-2104(00)70103-X]
24. Schafer E. Effect of physical vapor deposition on cutting efficiency of nickel-titanium files. J Endod 2002;28(12):800-2. [DOI:10.1097/00004770-200212000-00002]
25. Adini AR, Feldman Y, Cohen SR, Rapoport L, Moshkovich A, Redlich M, et al. Alleviating fatigue and failure of NiTi endodontic files by a coating containing inorganic fullerenelike WS2 nanoparticles. J Mater Res 2011;26(10):1234-1242. [DOI:10.1557/jmr.2011.52]
26. Peters LB, Wesselink PR. Periapical healing of endodontically treated teeth in one and two visits obturated in the presence or absence of detectable microorganisms. Int Endod J 2002;35(8):660-7. [DOI:10.1046/j.1365-2591.2002.00541.x]
27. Peters LB, Wesselink PR, Moorer WR. The fate and the role of bacteria left in root dentinal tubules. Int Endod J 1995;28(2):95-9. [DOI:10.1111/j.1365-2591.1995.tb00166.x]
28. Hulsmann M, Heckendorff M, Lennon A. Chelating agents in root canal treatment: mode of action and indications for their use. Int Endod J 2003;36(12):810-30. [DOI:10.1111/j.1365-2591.2003.00754.x]
29. Paque F, Boessler C, Zehnder M. Accumulated hard tissue debris levels in mesial roots of mandibular molars after sequential irrigation steps. Int Endod J 2011;44(2):148-53. [DOI:10.1111/j.1365-2591.2010.01823.x]
30. Ray HA, Trope M. Periapical status of endodontically treated teeth in relation to the technical quality of the root filling and the coronal restoration. Int Endod J 1995;28(1):12-8. [DOI:10.1111/j.1365-2591.1995.tb00150.x]
31. Lazarski MP, Walker WA, 3rd, Flores CM, Schindler WG, Hargreaves KM. Epidemiological evaluation of the outcomes of nonsurgical root canal treatment in a large cohort of insured dental patients. J Endod 2001;27(12):791-6. [DOI:10.1097/00004770-200112000-00021]
32. Kytridou V, Gutmann JL, Nunn MH. Adaptation and sealability of two contemporary obturation techniques in the absence of the dentinal smear layer. Int Endod J 1999;32(6):464- 74. [DOI:10.1046/j.1365-2591.1999.00248.x]
33. Wu MK, Wesselink PR. Endodontic leakage studies reconsidered. Part I. Methodology, application and relevance. Int Endod J 1993;26(1):37-43. [DOI:10.1111/j.1365-2591.1993.tb00540.x]
34. Siqueira JF, Jr., Rocas IN, Santos SR, Lima KC, Magalhaes FA, de Uzeda M. Efficacy of instrumentation techniques and irrigation regimens in reducing the bacterial population within root canals. J Endod 2002;28(3):181-4. [DOI:10.1097/00004770-200203000-00009]
35. Kishen A, Upadya M, Tegos GP, Hamblin MR. Efflux pump inhibitor potentiates antimicrobial photodynamic inactivation of Enterococcus faecalis biofilm. Photochem Photobiol 2010;86(6):1343-9. [DOI:10.1111/j.1751-1097.2010.00792.x]
36. Pagonis TC, Chen J, Fontana CR, Devalapally H, Ruggiero K, Song X, et al. Nanoparticle-based endodontic antimicrobial photodynamic therapy. J Endod 2010;36(2):322- 8. [DOI:10.1016/j.joen.2009.10.011]
37. Johnston HJ, Hutchison G, Christensen FM, Peters S, Hankin S, Stone V. A review of the in vivo and in vitro toxicity of silver and gold particulates: particle attributes and biological mechanisms responsible for the observed toxicity. Crit Rev Toxicol 2010;40(4):328-46. [DOI:10.3109/10408440903453074]
38. Peciuliene V, Reynaud AH, Balciuniene I, Haapasalo M. Isolation of yeasts and enteric bacteria in root-filled teeth with chronic apical periodontitis. Int Endod J 2001;34(6):429-34. [DOI:10.1046/j.1365-2591.2001.00411.x]
39. Tanomaru JM, Leonardo MR, Tanomaru Filho M, Bonetti Filho I, Silva LA. Effect of different irrigation solutions and calcium hydroxide on bacterial LPS. Int Endod J 2003;36(11):733-9. [DOI:10.1046/j.1365-2591.2003.00717.x]
40. Bystrom A, Claesson R, Sundqvist G. The antibacterial effect of camphorated paramonochlorophenol, camphorated phenol and calcium hydroxide in the treatment of infected root canals. Endod Dent Traumatol 1985;1(5):170-5. [DOI:10.1111/j.1600-9657.1985.tb00652.x]
41. Shrestha A, Shi Z, Neoh KG, Kishen A. Nanoparticulates for antibiofilm treatment and effect of aging on its antibacterial activity. J Endod 2010;36(6):1030-5. [DOI:10.1016/j.joen.2010.02.008]
42. Schilder H. Filling root canals in three dimensions. 1967. J Endod 2006;32(4):281-90. [DOI:10.1016/j.joen.2006.02.007]
43. Langeland K. Root canal sealants and pastes. Dent Clin North Am 1974;18(2):309-27.
44. Grossman LI, Oliet S, Carlos E, Rio D. Endodontic practice. 11th ed ed. Philadelphia: Lea & Febiger; 1988.
45. Schilder H, Goodman A, Aldrich W. The thermomechanical properties of gutta-percha. 3. Determination of phase transition temperatures for gutta-percha. Oral Surg Oral Med Oral Pathol 1974;38(1):109-14. [DOI:10.1016/0030-4220(74)90321-1]
46. Waltimo T, Brunner TJ, Vollenweider M, Stark WJ, Zehnder M. Antimicrobial effect of nanometric bioactive glass 45S5. J Dent Res 2007;86(8):754-7. [DOI:10.1177/154405910708600813]
47. Mohn D, Zehnder M, Imfeld T, Stark WJ. Radio-opaque nanosized bioactive glass for potential root canal application: evaluation of radiopacity, bioactivity and alkaline capacity. Int Endod J 2010;43(3):210-7. [DOI:10.1111/j.1365-2591.2009.01660.x]
48. Chen ZL, Wei W, Feng ZD, Liu XQ, Chen XL, Huang WX. [The development and in vitro experiment study of a bio-type root canal filling sealer using calcium phosphate cement]. Shanghai Kou Qiang Yi Xue 2007;16(5):530-3.
49. Koch K, Brave D, Nasseh A. A review of bioceramic technology in endodontics. roots 2012;4:6-12.
50. Chong B, Pitt Ford T. Root‐end filling materials: rationale and tissue response. Endod Top 2005;11(1):114-130. [DOI:10.1111/j.1601-1546.2005.00164.x]
51. Gartner AH, Dorn SO. Advances in endodontic surgery. Dent Clin North Am 1992;36(2):357-78.
52. Biggs JT, Benenati FW, Powell SE. Tenyear in vitro assessment of the surface status of three retrofilling materials. J Endod 1995;21(10):521-5. [DOI:10.1016/S0099-2399(06)80526-1]
53. Saghiri MA, Asgar K, Lotfi M, GarciaGodoy F. Nanomodification of mineral trioxide aggregate for enhanced physiochemical properties. Int Endod J 2012;45(11):979-88. [DOI:10.1111/j.1365-2591.2012.02056.x]
54. Krishnan PS, Joshi M, Bhargava P, Valiyaveettil S, He C. Effect of heterocyclic based organoclays on the properties of polyimide-clay nanocomposites. J Nanosci Nanotechnol 2005;5(7):1148-57. [DOI:10.1166/jnn.2005.171]
55. Cypes SH, Saltzman WM, Giannelis EP. Organosilicate-polymer drug delivery systems: controlled release and enhanced mechanical properties. J Control Release 2003;90(2):163-9. [DOI:10.1016/S0168-3659(03)00133-0]
56. Modareszadeh MR, Chogle SA, Mickel AK, Jin G, Kowsar H, Salamat N, et al. Cytotoxicity of set polymer nanocomposite resin root-end filling materials. Int Endod J 2011;44(2):154-61. [DOI:10.1111/j.1365-2591.2010.01825.x]
57. Alley BS, Kitchens GG, Alley LW, Eleazer PD. A comparison of survival of teeth following endodontic treatment performed by general dentists or by specialists. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;98(1):115-8. [DOI:10.1016/j.tripleo.2004.01.004]
58. Freitas RA, Jr. Nanodentistry. J Am Dent Assoc 2000;131(11):1559-65. [DOI:10.14219/jada.archive.2000.0084]
59. Hermann B. [On the reaction of the dental pulp to vital amputation and calxyl capping.]. Dtsch Zahnarztl Z 1952;7(24):1446-1447.
60. Ostby BN. The role of the blood clot in endodontic therapy. An experimental histologic study. Acta Odontol Scand 1961;19:324-53. [DOI:10.3109/00016356109043395]
61. Hargreaves K, Law A. Regenerative endodontics. In: Pathways of the pulp. St Louis: Mosby Elsevier; 2011. p. 602-19. [DOI:10.1016/B978-0-323-06489-7.00016-3]
62. Dundar M, Ozcan M, Comlekoglu ME, Sen BH. Nanoleakage inhibition within hybrid layer using new protective chemicals and their effect on adhesion. J Dent Res 2011;90(1):93-8. [DOI:10.1177/0022034510382547]
63. Fioretti F, Mendoza-Palomares C, Avoaka-Boni MC, Ramaroson J, Bahi S, Richert L, et al. Nano-odontology: nanostructured assemblies for endodontic regeneration. J Biomed Nanotechnol 2011;7(3):471-5. [DOI:10.1166/jbn.2011.1312]
64. Brauer DS, Hilton JF, Marshall GW, Marshall SJ. Nano- and micromechanical properties of dentine: Investigation of differences with tooth side. J Biomech 2011;44(8):1626-9. [DOI:10.1016/j.jbiomech.2011.03.004]
65. Smith IO, Liu XH, Smith LA, Ma PX. Nanostructured polymer scaffolds for tissue engineering and regenerative medicine. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2009;1(2):226-36. [DOI:10.1002/wnan.26]